{"id":36,"date":"2018-02-05T10:53:41","date_gmt":"2018-02-05T10:53:41","guid":{"rendered":"https:\/\/biotecnologiemicrobiche.wordpress.com\/?page_id=36"},"modified":"2026-01-15T14:35:28","modified_gmt":"2026-01-15T13:35:28","slug":"papers","status":"publish","type":"page","link":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/?page_id=36","title":{"rendered":"Papers"},"content":{"rendered":"<div class=\"entry-content\">\n<div class=\"entry-content\">\n<p><strong>2026<\/strong><\/p>\n<ol>\n<li>Yushchuk O, R\u00fcckert-Reed C, Busche T, Marinelli F, Kalinowski J. <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s13353-025-01035-6\">Updated sequence of ramoplanin biosynthetic gene cluster from <em>Actinoplanes ramoplaninifer<\/em> ATCC 33,076<\/a>. J Appl Genet. 2026 Jan 7. doi: 10.1007\/s13353-025-01035-6. Epub ahead of print. PMID: 41499035.<\/li>\n<\/ol>\n<p><strong>2025<\/strong><\/p>\n<ol>\n<li>Mellere, L.; Bava, A.; Armengaud, J.; Berini, F.; Marinelli, F.; Varese, G.C.; Spina, F.; Beltrametti, F. <a href=\"https:\/\/www.mdpi.com\/2309-608X\/11\/12\/890\">Unravelling the Potential of Fungal Division of Labour in the Laccase<\/a> Producer\u00a0<i>Coriolopsis trogii<\/i>\u00a0MUT3379 Through Protoplast Formation and Regeneration.\u00a0<em>J. Fungi<\/em>\u00a0<b>2025<\/b>,\u00a0<em>11<\/em>, 890. https:\/\/doi.org\/10.3390\/jof11120890<\/li>\n<li>Yushchuk O, Berini F, Zhong L, R\u00fcckert-Reed C, Bernasconi E, Bartolone L, Busche T, Kalinowski J, S\u00fcssmuth RD, Marinelli F. <a href=\"https:\/\/www.nature.com\/articles\/s42004-025-01534-x\">A rare peptide scaffold in kineomicins, the glycopeptide antibiotics produced by Actinokineospora auranticolor DSM 44650<\/a>. Commun Chem. 2025 May 3;8(1):134. doi: 10.1038\/s42004-025-01534-x. PMID: 40319198; PMCID: PMC12049478.<\/li>\n<li>Bisaccia M, Berini F, Marinelli F, Binda E. Emerging <a href=\"https:\/\/www.mdpi.com\/2079-6382\/14\/4\/394\">Trends in Antimicrobial Resistance in Polar Aquatic Ecosystems<\/a>. Antibiotics (Basel). 2025 Apr 10;14(4):394. doi: 10.3390\/antibiotics14040394. PMID: 40298543; PMCID: PMC12024378.<\/li>\n<li>Melissa B, Elisa B, Gabriella C, Maurizio A, Ombretta DA, Andrea DC, Eckert EM, Flavia M. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11788576\/\">Bacterial Diversity of Marine Biofilm Communities in Terra Nova Bay (Antarctica) by Culture-Dependent and -Independent Approaches<\/a>. Environ Microbiol. 2025 Feb;27(2):e70045. doi: 10.1111\/1462-2920.70045. PMID: 39895061; PMCID: PMC11788576.<\/li>\n<\/ol>\n<p><strong>2024<\/strong><\/p>\n<ol>\n<li>Stepanyshyn A, R\u00fcckert-Reed C, Busche T, Yaruta B, Andreo-Vidal A, Marinelli F, Kalinowski J, Yushchuk O. Complete Genome Assembly of\u00a0<i>Amycolatopsis bartoniae<\/i>\u00a0DSM 45807<sup>T<\/sup>\u00a0<a href=\"https:\/\/www.mdpi.com\/2073-4425\/15\/12\/1651\">Allows the Characterization of a Novel Glycopeptide Biosynthetic Gene Cluster.<\/a> Genes (Basel). 2024 Dec 22;15(12):1651. doi: 10.3390\/genes15121651. PMID: 39766918; PMCID: PMC11727664.<\/li>\n<li>Montali A, Berini F, Gamberoni F, Armenia I, Saviane A, Cappellozza S, Gornati R, Bernardini G, Marinelli F, Tettamanti G. <a href=\"https:\/\/www.mdpi.com\/2075-4450\/15\/11\/886\">In vivo efficacy of a nanoconjugated glycopeptide antibiotic in silkworm larvae infected by\u00a0<i>Staphylococcus aureus<\/i><\/a>. Insects 2024, 15, 886. https:\/\/doi.org\/10.3390\/insects15110886<\/li>\n<li>Yushchuk, O.; Zhukrovska, K.; Binda, E.; Marinelli, F. <a href=\"https:\/\/www.mdpi.com\/2311-5637\/10\/11\/544\">Unraveling the Biosynthetic Logic Behind the Production of Ramoplanin and Related Lipodepsipeptide Antibiotics<\/a>. <em>Fermentation<\/em>\u00a0<b>2024<\/b>,\u00a0<em>10<\/em>, 544. https:\/\/doi.org\/10.3390\/fermentation10110544<\/li>\n<li>Mellere L, Bellasio M, Berini F, Marinelli F, Armengaud J, Beltrametti F.\u00a0<i>Coriolopsis trogii<\/i>\u00a0MUT3379: <a href=\"https:\/\/www.mdpi.com\/2311-5637\/10\/7\/376\">A novel cell factory for high-yield laccase production<\/a>. Fermentation 2024, 10:376. doi: 10.3390\/fermentation10070376.<\/li>\n<li>Mi\u0161kovsk\u00e1 A, Michailidu J, Kolouchov\u00e1 IJ, Barone L, Gornati R, Montali A, Tettamanti G, Berini F, Marinelli F, Mas\u00e1k J, \u010cejkov\u00e1 A, Ma\u0165\u00e1tkov\u00e1 O. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0882401024000809?via%3Dihub\">Biological activity of silver nanoparticles synthesized using viticultural waste.<\/a> Microb Pathog. 2024 Mar 12;190:106613. doi: 10.1016\/j.micpath.2024.106613. Epub ahead of print. PMID: 38484919.<\/li>\n<li>Berini F, Montali A, Liguori R, Venturini G, Bonelli M, Shaltiel-Harpaz L, Reguzzoni M, Siti M, Marinelli F, Casartelli M, Tettamanti G. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ps.8045\">Production and characterization of Trichoderma asperellum chitinases and their use in synergy with Bacillus thuringiensis for lepidopteran control.<\/a> Pest Manag Sci. 2024 Feb 26. doi: 10.1002\/ps.8045. Epub ahead of print. PMID: 38407453.<\/li>\n<li>Yushchuk O, Binda E, R\u00fcckert-Reed C, Berini F, Fedorenko V, Kalinowski J, Marinelli F.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38190227\/\"><i>Actinoplanes oblitus<\/i>\u00a0sp. nov., producing the glycopeptide antibiotic A477<\/a>. Int J Syst Evol Microbiol. 2024 Jan;74(1). doi: 10.1099\/ijsem.0.006225. PMID: 38190227.<\/li>\n<li>Zhukrovska K, Binda E, Fedorenko V, Marinelli F, Yushchuk O. <a href=\"https:\/\/www.mdpi.com\/2079-6382\/13\/2\/115\">The Impact of Heterologous Regulatory Genes from Lipodepsipeptide Biosynthetic Gene Clusters on the Production of Teicoplanin and A40926<\/a>. <em>Antibiotics<\/em>\u00a0<b>2024<\/b>,\u00a0<em>13<\/em>, 115. https:\/\/doi.org\/10.3390\/antibiotics13020115<\/li>\n<\/ol>\n<p><strong>2023<\/strong><\/p>\n<\/div>\n<div class=\"entry-content\">\n<ol>\n<li>Bisaccia M, Binda E, Rosini E, Caruso G, Dell&#8217;Acqua O, Azzaro M, Lagan\u00e0 P, Tedeschi G, Maffioli EM, Pollegioni L, Marinelli F. <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2023.1078382\/full\">A novel promising laccase from the psychrotolerant and halotolerant Antarctic marine <i>Halomonas<\/i>\u00a0sp. M68 strain<\/a>. Front Microbiol. 2023 Feb 10;14:1078382. doi: 10.3389\/fmicb.2023.1078382. PMID: 36846806; PMCID: PMC9950745.<\/li>\n<li>Andreo-Vidal, A.; Yushchuk, O.; Marinelli, F.; Binda, E.<a href=\"https:\/\/www.mdpi.com\/2079-6382\/12\/4\/641\"> Cross-Talking of Pathway-Specific Regulators in Glycopeptide Antibiotics (Teicoplanin and A40926) Production<\/a>.\u00a0<em>Antibiotics<\/em>\u00a0<b>2023<\/b>,\u00a0<em>12<\/em>, 641. https:\/\/doi.org\/10.3390\/antibiotics12040641<\/li>\n<\/ol>\n<p><strong>2022<\/strong><\/p>\n<ol>\n<li>Yushchuk, O.; Zhukrovska, K.; Ostash, B.; Fedorenko, V.; Marinelli, F. <a href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/24\/15713\">Heterologous Expression Reveals Ancient Properties of Tei3\u2014A VanS Ortholog from the Teicoplanin Producer\u00a0<i>Actinoplanes<\/i><i>teichomyceticus<\/i>.<\/a>\u00a0<em>Int. J. Mol. Sci.<\/em>\u00a02022,\u00a0<em>23<\/em>, 15713. https:\/\/doi.org\/10.3390\/ijms232415713<\/li>\n<li>Yushchuk O, Binda E, Fedorenko V, Marinelli F. <a href=\"https:\/\/www.mdpi.com\/2073-4425\/13\/11\/1960\">Occurrence of\u00a0<i>vanHAX<\/i>\u00a0and Related Genes beyond the\u00a0<i>Actinobacteria\u00a0<\/i>Phylum.\u00a0<em>Genes<\/em>.<\/a> 2022; 13(11):1960. https:\/\/doi.org\/10.3390\/genes13111960<\/li>\n<li>Montali A, Berini F, Saviane A, Cappellozza S, Marinelli F, Tettamanti G. <a href=\"https:\/\/www.mdpi.com\/2075-4450\/13\/8\/748\">A\u00a0<i>Bombyx mori<\/i>\u00a0Infection Model for Screening Antibiotics against\u00a0<i>Staphylococcus epidermidis<\/i>. Insects<\/a>. 2022 Aug 19;13(8):748. doi: 10.3390\/insects13080748.<\/li>\n<li>Hoyos P, Perona A, Bavaro T, Berini F, Marinelli F, Terreni M, Hern\u00e1iz MJ. <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.accounts.2c00136\">Biocatalyzed Synthesis of Glycostructures with Anti-infective Activity.<\/a> Acc Chem Res. 2022 Sep 6;55(17):2409-2424. doi: 10.1021\/acs.accounts.2c00136.<\/li>\n<li>Yushchuk O, Zhukrovska K, Berini F, Fedorenko V, Marinelli F.<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fchem.2022.858708\/full\"> Genetics Behind the Glycosylation Patterns in the Biosynthesis of Dalbaheptides.<\/a> Front Chem. 2022 Mar 24;10:858708. doi: 10.3389\/fchem.2022.858708.<\/li>\n<li>Berini F, Orlandi V, Gornati R, Bernardini G, Marinelli F. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0734975022000441?via%3Dihub\">Nanoantibiotics to fight multidrug resistant infections by Gram-positive bacteria: hope or reality?<\/a> Biotechnol Adv. 2022 Jul-Aug;57:107948. doi: 10.1016\/j.biotechadv.2022.107948. Epub 2022 Mar 23. PMID: 35337933.<\/li>\n<li>\n<div>Mellere L., Bava A., Capozzoli C, Branduardi P, Berini F, Beltrametti F (2022)<a href=\"https:\/\/www.mdpi.com\/2079-6382\/11\/1\/24\">. Strain improvement and strain maintenance revisited. The use of\u00a0<i>Actinoplanes teichomyceticus<\/i>\u00a0ATCC 31121 protoplasts in the identification of candidates for enhanced teicoplanin production.<\/a> Antibiotics, 11(1), 24. doi:\u00a010.3390\/antibiotics11010024<\/div>\n<\/li>\n<\/ol>\n<p><strong>2021<\/strong><\/p>\n<ol>\n<li>Andreo-Vidal A, Binda E, Fedorenko V, Marinelli F, Yushchuk O. (2021).\u00a0 <a href=\"https:\/\/www.mdpi.com\/2079-6382\/10\/12\/1533\">Genomic Insights into the Distribution and Phylogeny of Glycopeptide Resistance Determinants within the <i>Actinobacteria<\/i> Phylum.<\/a> Antibiotics (Basel). 10(12):1533. doi: 10.3390\/antibiotics10121533<\/li>\n<li>Berini F, Orlandi VT, Gamberoni F, Martegani E, Armenia I, Gornati R, Bernardini G, Marinelli F (2021).<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2021.657431\/full\"> Antimicrobial activity of nanoconjugated glycopeptide antibiotics and their effect on<i>Staphylococcus aureus<\/i>\u00a0biofilm.<\/a> Front Microbiol, 12, 657431. doi:\u00a010.3389\/fmicb.2021.657431.<\/li>\n<li>\n<div>Martini MC, Berini F, Ausec L, Casciello C, Vacca C, Pistorio M, Lagares A, Mandic-Mulec I, Marinelli F, Del Papa F (2021). <a href=\"https:\/\/hrcak.srce.hr\/clanak\/392324\">Identification and characterization of a novel plasmid-encoded laccase-like multicopper oxidase from\u00a0<i>Ochrobactrum\u00a0<\/i>sp. BF15 isolated from an on-farm bio-purification system.<\/a> Food Tech Biotech, 59(4), 519-529. doi: 10.17113\/ftb.59.04.21.7253.<\/div>\n<\/li>\n<li>Binda, E., Berini, F., Marinelli, F., Bava, A., Beltrametti, F. (2021) <a href=\"https:\/\/www.mdpi.com\/2311-5637\/7\/3\/140\">Heterogeneous A40926 Self-Resistance Profile in <i>Nonomuraea gerenzanensis<\/i>\u00a0Population Informs Strain Improvement<\/a>. Fermentation\u00a0<em>7<\/em>, 140. doi.org\/10.3390\/fermentation7030140<\/li>\n<li>Jezkova Z, Binda E, Potocar T, Marinelli F, Halecky M, Branyik T. (2021) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34003399\/\">Laboratory scale cultivation of <em>Salinispora tropica<\/em> in shake flasks and mechanically stirred bioreactors.<\/a> Biotechnol Lett. doi: 10.1007\/s10529-021-03121-1. Epub ahead of print. PMID: 34003399.<\/li>\n<li>Yushchuk O, Vior NM, Andreo-Vidal A, Berini F, R\u00fcckert C, Busche T, Binda E, Kalinowski J, Truman AW, Marinelli F. (2021)\u00a0 <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.1c00170\">Genomic-Led Discovery of a Novel Glycopeptide Antibiotic by <i>Nonomuraea coxensis<\/i> DSM 45129<\/a>. ACS Chem Biol.\u00a0 doi: 10.1021\/acschembio.1c00170. Epub ahead of print. PMID: 33913701.<\/li>\n<li>Marinelli F, Alifano P, Landini P, Visca P. (2021) <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2021.672517\/full\">Editorial: XXXIII SIMGBM Congress 2019 &#8211; Antimicrobials and Host-Pathogen Interactions<\/a>.\u00a0Front. Microbiol. https:\/\/doi.org\/10.3389\/fmicb.2021.67251.<\/li>\n<\/ol>\n<p><strong>2020<\/strong><\/p>\n<div class=\"article-header-container\">\n<ol>\n<li style=\"text-align: justify;\"><span style=\"color: var(--color-text);\">Berini F, Marinelli F., Binda E. (2020) <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2020.01958\/full\">Streptomycetes: Attractive Hosts for Recombinant Protein Production<\/a>. Front. Microbiol 11:1958. doi: 10.3389\/fmicb.2020.01958.<\/span><\/li>\n<li>Dalmastri C, Gastaldo L, Berini F, Marinelli F, Marcone GL. (2020). <a href=\"https:\/\/www.microbiologyresearch.org\/content\/journal\/ijsem\/10.1099\/ijsem.0.004348#tab2\">Description of the bacterial RNA polymerase inhibitor GE23077-producer\u00a0<i>Actinomadura\u00a0<\/i>sp. NRRL B-65521T as\u00a0<i>Actinomadura lepetitiana\u00a0<\/i>sp. nov.<\/a> Int. J. Syst. Evol. Microbiol. 70(8):4782-4790. doi: 10.1099\/ijsem.0.004348<\/li>\n<li style=\"text-align: justify;\">Yushchuk O, Binda E, Marinelli F. (2020) <a href=\"https:\/\/doi.org\/10.3389\/fmicb.2020.01173\">Glycopeptide Antibiotic Resistance Genes: Distribution and Function in the Producer Actinomycetes<\/a>. Front. Microbiol doi.org\/10.3389\/fmicb.2020.01173.<\/li>\n<li style=\"text-align: justify;\">Montali A, Berini F, Brivio MF, Mastore M, Saviane A, Cappellozza S,Marinelli F, Tettamanti G. (2020) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32512807\/\">A Silkworm Infection Model for In Vivo Study of Glycopeptide Antibiotics<\/a>. Antibiotics (Basel). 9:E300. doi: 10.3390\/antibiotics9060300.<\/li>\n<li style=\"text-align: justify;\">Yushchuk O, Ostash B, Truman AW, Marinelli F, Fedorenko V. (2020) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32076781\">Teicoplanin biosynthesis: unraveling the interplay of structural, regulatory, and resistance genes. Appl Microbiol Biotechnol.<\/a> doi: 10.1007\/s00253-020-10436-y. Epub ahead of print. PMID: 32076781.<\/li>\n<li style=\"text-align: justify;\">Yushchuk O, Vidal A-A, Marcone GL, Bibb M, Marinelli F, Binda E. (2020) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6985074\/\">New Molecular Tools for Regulation and Improvement of A40926 Glycopeptide Antibiotic Production in Nonomuraea gerenzanensis ATCC 39727.<\/a>Front. Microbiol. 11:8. doi: 10.3389\/fmicb.2020.00008.<\/li>\n<li style=\"text-align: justify;\">Yushchuk O, Homoniuk V, Ostash B, Marinelli F, Fedorenko V. (2020). <a href=\"https:\/\/www.nature.com\/articles\/s41429-019-0274-9\">Genetic insights into the mechanism of teicoplanin self-resistance in Actinoplanes teichomyceticus<\/a>. J. Antibiot. 73:255-259\u00a0doi: 10.1038\/s41429-019-0274-9.<\/li>\n<li style=\"text-align: justify;\">Yushchuk O, Homoniuk V, Datsiuk Y, Ostash B, Marinelli F, Fedorenko V. (2020) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31912451\">Development of a gene expression system for the uncommon actinomycete Actinoplanes rectilineatus NRRL B-16090.<\/a><span class=\"jrnl\" style=\"color: var(--color-text);\" title=\"Journal of applied genetics\">J Appl Genet<\/span><span style=\"color: var(--color-text);\">. doi: 10.1007\/s13353-019-00534-7.\u00a0<\/span><\/li>\n<\/ol>\n<\/div>\n<p style=\"text-align: justify;\"><strong>2019<\/strong><\/p>\n<\/div>\n<div class=\"entry-content\">\n<div class=\"supp\">\n<ol>\n<li>\n<p class=\"title\" style=\"text-align: justify;\">Marcone GL, Binda E, Rosini E, Abbondi M, Pollegioni L. (2019) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31849918\">Antibacterial Properties of D-Amino Acid Oxidase: Impact on the Food Industry. <\/a><span class=\"jrnl\" style=\"color: var(--color-text);\" title=\"Frontiers in microbiology\">Front Microbiol<\/span><span style=\"color: var(--color-text);\">. 10:2786.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"title\" style=\"text-align: justify;\"><span style=\"color: var(--color-text);\">F. Berini, M. Casartelli, A. Montali, M. Reguzzoni, G. Tettamanti, F. Marinelli. (2019)\u00a0<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31275279\">Metagenome-Sourced Microbial Chitinases as Potential Insecticide Proteins. <\/a><span class=\"jrnl\" title=\"Frontiers in microbiology\">Front Microbiol<\/span>. 10:1358.<\/p>\n<\/li>\n<li style=\"text-align: justify;\">O. Yushchuk, L. Horbal, B. Ostash, F. Marinelli, W. Wohlleben, E. Stegmann, V. Fedorenko. (2019)\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30937499\">Regulation of teicoplanin biosynthesis: refining the roles of tei cluster-situated regulatory genes.\u00a0<\/a><span class=\"jrnl\" title=\"Applied microbiology and biotechnology\">Appl Microbiol Biotechnol<\/span>. 103(10):4089-4102.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"supp\">\n<p class=\"details\">\n<\/div>\n<div class=\"entry-content\">\n<p style=\"text-align: justify;\"><strong>2018<\/strong><\/p>\n<\/div>\n<div class=\"entry-content\">\n<div class=\"supp\">\n<ol>\n<li style=\"text-align: justify;\"><span lang=\"EN-US\">I. Armenia, G.L. Marcone, F. Berini, V.T. Olandi, C. Pirrone, E. Martegani, R. Gornati , G. Bernardini, F. Marinelli. (2018) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30386305\">Magnetic Nanoconjugated Teicoplanin: A Novel Tool for Bacterial Infection Site Targeting.<\/a>. <span class=\"jrnl\" title=\"Frontiers in microbiology\">Front Microbiol<\/span>. 9:2270.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\">E. Binda, P. Cappelletti, F. Marinelli, G.L. Marcone. (2018)\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29693566\">Specificity of Induction of Glycopeptide Antibiotic Resistance in the Producing Actinomycetes.\u00a0<\/a><span class=\"jrnl\" title=\"Antibiotics (Basel, Switzerland)\">Antibiotics <\/span><span class=\"jrnl\" title=\"Antibiotics (Basel, Switzerland)\">(Basel).<\/span>\u00a025(2).\u00a0<a href=\"https:\/\/www.mdpi.com\/2079-6382\/7\/2\/36\">https:\/\/doi: 10.3390\/antibiotics7020036\u00a0<\/a><\/li>\n<li style=\"text-align: justify;\">G.L. Marcone, E. Binda, F. Berini, F. Marinelli. (2018)\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29454983\">Old and new glycopeptide antibiotics: From product to gene and back in the post-genomic era.\u00a0<\/a><span class=\"jrnl\" title=\"Biotechnology advances\">Biotechnol Adv<\/span>. 36(2):534-554. <a href=\"https:\/\/doi.org\/10.1016\/j.biotechadv.2018.02.009\">https\/\/doi: 10.1016\/j.biotechadv.2018.02.009<\/a>.<\/li>\n<li style=\"text-align: justify;\">F. Berini, M. Verce, L. Ausec, E. Rosini, F. Tonin, L. Pollegioni, I. Mandic-Mulec. (2018). Isolation and characterization of a heterologously expressed bacterial laccase from the anaerobe <em>Geobacter metallireducens<\/em>. Appl Microbiol Biotechnol.\u00a0102(5):2425-2439\u00a0\u00a0<a href=\"https:\/\/doi.org\/10.1007\/s00253-018-8785-z\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1007\/s00253-018-8785-z<\/a><\/li>\n<li style=\"text-align: justify;\">F. Berini, C. Katz, N. Gruzdev, M. Casartelli, G. Tettamanti, F. Marinelli. (2018) Microbial and viral chitinases: Attractive biopesticides for integrated pest management. Biotechnol Adv. 2018 May &#8211; Jun;36(3):818-838.<a href=\"https:\/\/doi.org\/ 10.1016\/j.biotechadv.2018.01.002\" target=\"_blank\" rel=\"noopener noreferrer\">\u00a0https:\/\/doi.org\/ 10.1016\/j.biotechadv.2018.01.002<\/a><\/li>\n<\/ol>\n<\/div>\n<p style=\"text-align: justify;\"><strong>2017<\/strong><\/p>\n<ol style=\"text-align: justify;\">\n<li>F. Berini, C. Casciello, G.L. Marcone, F. Marinelli. (2017) Metagenomics: novel enzymes from nonculturable microbes. FEMS Microbiol Lett. 364(21) <a href=\"https:\/\/doi.org\/10.1093\/femsle\/fnx211\">https:\/\/doi.org\/10.1093\/femsle\/fnx211<\/a><\/li>\n<li>G.L Marcone, E. Binda, M. Reguzzoni, L. Gastaldo, C. Dalmastri, F. Marinelli. (2017) <a href=\"http:\/\/10.1099\/ijsem.0.002281\">Classification of <em>Actinoplanes<\/em> sp. ATCC 33076, an actinomycete that produces the glycolipodepsipeptide antibiotic ramoplanin, as <em>Actinoplanes ramoplaninifer<\/em> sp. nov<\/a><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28905706\">.<\/a> Int J Syst Evol Microbiol. 67(10):4181-4188.\u00a0<a href=\"https:\/\/doi.org\/10.1099\/ijsem.0.002281\">10.1099\/ijsem.0.002281<\/a><\/li>\n<li>L. Ausec, F. Berini, C. Casciello, M.S. Cretoiu, J.D. van Elsas, F. Marinelli, I. Mandic-Mulec. (2017). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28589226\">The first acidobacterial laccase-like multicopper oxidase revealed by metagenomics shows high salt and thermo-tolerance.<\/a> Appl Microbiol Biotechnol. 101(15):6261-6276.\u00a0 <a href=\"https:\/\/doi.org\/10.1007\/s00253-017-8345-y\">https:\/\/doi.org\/10.1007\/s00253-017-8345-y<\/a><\/li>\n<li>F. Berini, I. Presti, F. Beltrametti, M. Pedroli, K.J. V\u00e5rum, L. Pollegioni, S. Sj\u00f6ling, F. Marinelli. (2017). Production and characterization of a novel antifungal chitinase identified by functional screening of a suppressive-soil metagenome. Microb. Cell. Fact. 16:16. <a href=\"http:\/\/dx.doi.org\/10.1186\/s12934-017-0634-8\">http:\/\/dx.doi.org\/10.1186\/s12934-017-0634-8<\/a><\/li>\n<li>C. Casciello, F. Tonin, F. Berini, E. Fasoli, F. Marinelli, L. Pollegioni, E. Rosini. (2017). A valuable peroxidase activity from the novel species <em>Nonomuraea gerenzanensis<\/em> growing on alkali lignin. Biotechnol Rep. 13: 49-57. <a href=\"http:\/\/dx.doi.org\/10.1016\/j.btre.2016.12.005\">\u00a0http:\/\/dx.doi.org\/10.1016\/j.btre.2016.12.005<\/a><\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><strong>2016<\/strong><\/p>\n<ol style=\"text-align: justify;\">\n<li>E. Binda, L. Carrano, G.L. Marcone, F. Marinelli. (2016). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27311671\">Extraction and Analysis of Peptidoglycan Cell Wall Precursors.<\/a> Methods Mol Biol.1440:153-70.<\/li>\n<li>C. Dalmastri, L. Gastaldo, G.L. Marcone, E. Binda, T. Congiu, F. Marinelli. (2016). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26944798\">Classification of <i>Nonomuraea<\/i> sp. ATCC 39727, an actinomycete that produces the glycopeptide antibiotic A40926, as <i>Nonomuraea gerenzanensis<\/i> sp. nov.<\/a> Int J Syst Evol Microbiol. 66(2):912-21.<\/li>\n<li>B. Rioseras, P. Yag\u00fce, M.T. L\u00f3pez-Garc\u00eda, N. Gonzalez-Qui\u00f1onez, E. Binda, F. Marinelli, A. Manteca. (2016). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26867711\">Characterization of SCO4439, a D-alanyl-D-alanine carboxypeptidase involved in spore cell wall maturation, resistance, and germination in <i>Streptomyces coelicolor<\/i>.<\/a> Sci Rep. 6:21659.<\/li>\n<li>F. Berini, S. Caccia, E. Franzetti, T. Congiu, F. Marinelli, M. Casartelli, G. Tettamanti. (2016). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26179981\">Effects of <i>Trichoderma viride<\/i> chitinases on the peritrophic matrix of Lepidoptera.<\/a> Pest Manag Sci. 72(5):980-9.<\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><b>2015<\/b><\/p>\n<ol style=\"text-align: justify;\">\n<li>A. Gallazzi, B. Branska, F. Marinelli, P. Patakova. (2015). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26471284\">Continuous production of n-butanol by <i>Clostridium pasteurianum<\/i> DSM 525 using suspended and surface-immobilized cells.<\/a> J Biotechnol. 20;216:29-35.<\/li>\n<li>L. Carrano, M. Abbondi, P. Turconi, G. Candiani, F. Marinelli. (2015). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26346738\">A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic Screening.<\/a> Biomed Res Int. 2015;2015:419383.<\/li>\n<li>F. Marinelli, O. Genilloud, V. Fedorenko, E.Z. Ron. (2015) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26345672\">Specialized Bioactive Microbial Metabolites: From Gene to Product.<\/a> Biomed Res Int. 2015:276964.<\/li>\n<li>V. Fedorenko, O. Genilloud, L. Horbal, G.L. Marcone, F. Marinelli, Y. Paitan, E.Z. Ron. (2015). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26339625\">Antibacterial Discovery and Development: From Gene to Product and Back.<\/a> Biomed Res Int. 2015:591349.<\/li>\n<li>M.S. Cretoiu, F. Berini, A.M. Kielak, F. Marinelli, J.D. van Elsas JD. (2015). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26040993\">A novel salt-tolerant chitobiosidase discovered by genetic screening of a metagenomic library derived from chitin-amended agricultural soil.<\/a> Appl Microbiol Biotechnol. 99(19):8199-215.<\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><b>2014<\/b><\/p>\n<ol style=\"text-align: justify;\">\n<li>\u00a0E. Binda, F. Marinelli, G. L. Marcone (2014). Old and New Glycopeptide Antibiotics: Action and Resistance. <em>Antibiotics<\/em><em>3:<\/em> 572-594;<\/li>\n<li>L. Horbal, A. Kobylyanskyy, A.W. Truman, N. Zaburranyi, B. Ostash, A. Luzhetskyy, F. Marinelli, V. Fedorenko (2014). The pathway-specific regulatory genes, <em>tei15<\/em>* and <em>tei16<\/em>*, are the master switches of teicoplanin production in <em>Actinoplanes teichomyceticus<\/em>. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25104028\">Appl Microbiol Biotechnol.<\/a>98: 9295-309;<\/li>\n<li>C. Temporini, T. Bavaro, S. Tengattini, I. Serra, G. Marrubini, E. Calleri, F. Fasanella, L. Piubelli,\u00a0F. Marinelli, L. Pollegioni, G. Speranza, G. Massolini, M. Terreni (2014). <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25282312\">Liquid chromatography-mass spectrometry structural characterization of neo glycoproteins aiding the rational design and synthesis of a novel glycovaccine for protection against Tuberculosis.<\/a>\u00a0J Chromatogr A. 9673: 01456-3;<\/li>\n<li>G.L. Marcone, E. Binda, L. Carrano, M. Bibb,\u00a0F. Marinelli (2014). Relationship between glycopeptide production and resistance in the actinomycete <em>Nonomuraea<\/em> sp. ATCC 39727. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24957828\">Antimicrob Agents Chemother.<\/a>58:5191-201;<\/li>\n<li>J. Tevino, C. Bayon, A. Ard\u00e0, F. Marinelli, R. Gandolfi, F. Molinari, J Jimenez-Barbero, M. J. Hernaiz (2014). New insights into glycopeptide antibiotic binding to cell wall precursors using SPR and NMR spectroscopy. Chem Eur. J. 20: 1-11;<\/li>\n<li>G.L. Marcone, F. Marinelli (2014). Glycopeptides: an old but up-to-date successful antibiotic class\u201d Chapter 5. In Marinelli F, Genilloud O. Antimicrobials New and Old Molecules in the Fight Against Multi-resistant Bacteria. vol. Unico, p. 85-107, Springer , ISBN: 9783642399688;<\/li>\n<li>H.A. Kirst, F. Marinelli (2014). Aminoglycoside antibiotics. Chapter 10. In: Marinelli F, Genilloud O. Antimicrobials New and Old Molecules in the Fight Against Multi-resistant Bacteria. vol. Unico, p. 193-207, Spinger, ISBN: 9783642399688;<\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><b>2013<\/b><\/p>\n<ol style=\"text-align: justify;\">\n<li>E. Binda, GL. Marcone, F. Berini, L. Pollegioni, F. Marinelli (2013). Streptomyces spp. as efficient expression system for a D,D-peptidase\/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance. BMC Biotechnol. 13:24;<\/li>\n<li>L. Piubelli, M. Campa, C. Temporini, E. Binda, F. Mangione, M. Amicosante, M. Terreni, F. Marinelli, L. Pollegioni (2013). Optimizing <em>Escherichia coli<\/em> as a protein expression platform to produce <em>Mycobacterium tuberculosis<\/em> immunogenic proteins. Microb Cell Fact. 12:115;<\/li>\n<li>K. Hjort, I. Presti, A. Elv\u00e4ng, F. Marinelli and S. Sj\u00f6ling (2013). Bacterial chitinase with phytopathogen control capacity from suppressive soil revealed by functional metagenomics. Appl. Microbiol. Biotechnol. 98: 2819\u20132828;<\/li>\n<li>L. Horbal, A. Kobylyanskyy, O. Uschuck, N. Zaburannyi, A. Luzhetskyy, B. Ostash, F. Marinelli, V. Fedorenko (2013). Evaluation of heterologous promoters for genetic analysis of <em>Actinoplanes teichomyceticus<\/em> \u2013 producer of teicoplanin, drug of last defense. Journal of Biotechnology. 168: 367-72;<\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><b>2012<\/b><\/p>\n<ol>\n<li style=\"text-align: justify;\">R. Gandolfi, F. Marinelli, E. Ragg, D. Romano, F. Molinari (2012). Chemoenzymatic deacylation of ramoplanin. Bioorg Med Chem Lett. 22(16):5283-7;<\/li>\n<li style=\"text-align: justify;\">E. Binda, GL. Marcone, L. Pollegioni, F. Marinelli (2012). Characterization of VanYn, a novel D,D-peptidase\/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance in <em>Nonomuraea<\/em> sp. ATCC 39727. FEBS J. 279(17):3203-13;<\/li>\n<li style=\"text-align: justify;\">F. Marinelli, F. Molinari (2012). \u201cLas fermentaciones en al produci\u00f2n de metabolitos secundarios de inter\u00e9s farmac\u00e9utico\u201d In J.M. S\u00e0nchez Montero, F. Ortega Ortiz de Apodaca, A. Doadrio Villarejo. Monograf\u00eca XXXV: Biocat\u00e0lisis aplicada a la obtenci\u00f2n de f\u00e0rmacos y productos de alto valor a\u00f1adido. p. 61-104, Madrid: Real Academia Nacional de Farmacia, ISBN: 9788493817275;<\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>2026 Yushchuk O, R\u00fcckert-Reed C, Busche T, Marinelli F, Kalinowski J. Updated sequence of ramoplanin biosynthetic gene cluster from Actinoplanes ramoplaninifer ATCC 33,076. J Appl Genet. 2026 Jan 7. doi: 10.1007\/s13353-025-01035-6. Epub ahead of print. PMID: 41499035. 2025 Mellere, L.; Bava, A.; Armengaud, J.; Berini, F.; Marinelli, F.; Varese, G.C.; Spina, F.; Beltrametti, F. Unravelling [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":185,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-36","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/pages\/36","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=36"}],"version-history":[{"count":12,"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/pages\/36\/revisions"}],"predecessor-version":[{"id":979,"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/pages\/36\/revisions\/979"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=\/wp\/v2\/media\/185"}],"wp:attachment":[{"href":"https:\/\/www.dbsv.uninsubria.it\/microbiotec\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=36"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}