PhD position:<\/b><\/p>\n
\u201cMolecular mechanisms underlying glutamatergic receptor dysfunctions in CDKL5 disorder<\/em>.\u201d<\/p>\n As part of the PhD program in Experimental and Translational Medicine at University of Insubria a project aimed at characterizing the molecular defects underlying synaptic and cognitive impairment in CDKL5 disorder is available. The focus of the project is to understand the role of CDKL5 in regulating glutamatergic receptor functions starting from a hitherto unknown CDKL5 interacting protein that was recently identified in our lab. The project will include phospho-proteomic approaches, molecular biology and imaging techniques making large use of primary neuronal cultures. Interested candidates should contact Prof. Kilstrup-Nielsen for further details.<\/p>\n \u201cApplicazione di tecniche di biologia computazionale per l’identificazione di pathway molecolari dipendenti da Mecp2 di rilevanza terapeutica<\/em>”<\/p>\n Come parte del programma del Dottorato di Ricerca in Medicina Sperimentale e Biotecnologie Mediche all\u2019Universit\u00e0 degli Studi di Milano nel Laboratorio di Biologia Molecolare (Dipartimento di Biotecnologie Mediche e Medicina Translazionale, BIOMETRA) della prof.ssa Nicoletta Landsberger \u00e8 disponibile un progetto volto all\u2019identificazione di nuovi target terapeutici per il trattamento della sindrome di Rett attraverso tecniche di biologia molecolare e computazionale applicate a popolazioni neuronali isolate da topi Mecp2 mutati.<\/p>\n Competenze richieste: Conoscenza delle principali tecniche di biologia molecolare, disponibilit\u00e0 a lavorare con piccoli roditori.<\/p>\n Contatti: nicoletta.landsberger@unimi.it<\/p>\n","protected":false},"excerpt":{"rendered":" PhD position: \u201cMolecular mechanisms underlying glutamatergic receptor dysfunctions in CDKL5 disorder.\u201d As part of the PhD program in Experimental and Translational Medicine at University of Insubria a project aimed at characterizing the molecular defects underlying synaptic and cognitive impairment in CDKL5 disorder is available. The focus of the project is to understand the role of … <\/p>\n